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Melaleuca alternifolia (leaf oil)

Tea tree oil

Diluted tea tree oil has modest support for mild to moderate acne: a 2026 meta-analysis of 7 studies found a reduction in severity, and in a 1990 trial 5% gel was slower than 5% benzoyl peroxide but caused fewer side effects. A 5% shampoo also cut dandruff in one trial, while evidence for nail fungus and head lice is weak.

Never swallow it, and never use it neat on skin: it is poisonous if eaten and a known cause of contact allergy, more so when the oil is old or oxidised.

A small amber bottle of tea tree oil beside tea tree leaves
At a glance
Last reviewed 10 October 2026
Evidence
Moderate
Best for
Mild to moderate acne
Typical form & use
5% gel or shampoo, applied to skin
Onset
4+ weeks
Safety
Poisonous if swallowed; can cause contact allergy. No interactions in our data.
Check with your medications →

What it's used for

Evidence is rated per use. The same ingredient can be strong for one thing and traditional for another.

UseEvidenceWhat the research shows
Mild to moderate acneCompare remedies for skin →Moderate

A 2026 meta-analysis of 7 studies (445 people) found tea tree oil was associated with lower acne severity than controls (pooled odds ratio 0.74, 95% CI 0.63 to 0.88), with mostly mild local side effects.

In the trial most often cited, 124 people used 5% tea tree oil gel or 5% benzoyl peroxide lotion: both cut inflamed and non-inflamed spots, benzoyl peroxide acted faster, and tea tree oil had fewer side effects. An earlier systematic review of randomised trials said more evidence was needed, and studies were small and short.3,2,4

DandruffCompare remedies for hair & nails →Limited

In 126 people with mild to moderate dandruff, a 5% tea tree oil shampoo used daily for 4 weeks improved the severity score by 41% against 11% for placebo shampoo, with no adverse effects reported. It was a single-blind trial, and we found no second trial to confirm it. The scaliness rating improved but not significantly.1

Fungal toenail infection (onychomycosis)Limited

In 117 people with culture-proven toenail infection, 100% tea tree oil twice daily for 6 months matched 1% clotrimazole solution: culture cure was 18% against 11%, and 60% against 61% had partial or full clinical improvement. Both were weak treatments, since most infections were not cleared. NCCIH says the amount and quality of research is not enough to reach any conclusion.5,8

Head liceLimited

In 123 people, a product containing tea tree oil plus lavender oil left 97.6% louse-free after three weekly applications, against 25% with a pyrethrin product. It was a combination product, so the result cannot be credited to tea tree oil alone, and NCCIH notes that it has only been tested with other ingredients. Plain tea tree oil for lice is untested by any trial we read.6,8

Skin generally (wounds, eczema, fungal skin infection)Traditional

The National Capital Poison Center says there is very little scientific evidence that tea tree oil works for most skin conditions. The 2023 systematic review of 46 randomised trials called the quality of research poor to modest, and said any local anti-inflammatory effect on skin needs more research.9,4

How much

Ranges below are what studies used and what supplements commonly contain. They are not a recommendation for you. Start at the low end.

Acne trial
5% tea tree oil gel2
The concentration compared with 5% benzoyl peroxide lotion in 124 people. Gels and washes are the tested forms; how often it was applied is not in the abstract we read.
Dandruff trial
5% shampoo, daily for 4 weeks1
Used daily for 4 weeks in the 126-person trial. Products vary, so check the tea tree oil percentage on the label.
Upper limit for skin
Avoid 25% or stronger on skin4,5
A systematic review of 46 trials found side effects were minor except where tea tree oil was applied topically at 25% or more. The toenail trial used neat oil twice daily for 6 months.
Timing · The dandruff shampoo was used daily. For acne, no source we read gives a schedule beyond the 5% gel strength.With food? · Not applicable: do not swallow it. NCCIH says it should not be swallowed, and the National Capital Poison Center calls it poisonous if swallowed.How long to trial · Judge acne and dandruff after about 4 weeks. Tea tree oil acted more slowly than benzoyl peroxide in the acne trial. Patch-test on a small area first, and stop if the skin becomes red, itchy or sore.

How people take it

5% gel or wash (acne)5% tea tree oilThe strength tested against benzoyl peroxide. Do not raise the strength: 25% and above caused more side effects in trials.
5% shampoo (dandruff)Daily for 4 weeks in the trialThe form tested against placebo shampoo. Shop products differ in tea tree oil content.
Neat (undiluted) oilNot recommendedA 100% oil was used on toenails in one trial, but most contact allergy reports involve the pure oil, so avoid it on skin.
Combination lice productThree applications, a week apart in the trialA tea tree oil and lavender oil product. Do not assume tea tree oil alone works.

Safety

Who should avoid
  • Swallowing it — poisonous; children have become confused, unsteady or unconscious
  • Children — keep out of reach and locked away; poison centres warn about ingestion
  • Old or oxidised oil — more likely to irritate and cause contact allergy
  • Undiluted oil on skin or in strengths of 25% or more — more side effects in trials
  • Known contact allergy to essential oils or turpentine — reactions often overlap
Known interactions
No interactions in our data. Absence of a flag is not clearance.

Questions people ask

Is tea tree oil good for hair and dandruff?

A 5% tea tree oil shampoo used daily for 4 weeks reduced dandruff severity by 41% against 11% for placebo in one trial of 126 people. It is a single trial, so the evidence is limited. We found no trial showing it helps hair growth or hair loss.

Does tea tree oil work for acne on the face?

It appears to help mild to moderate acne a little. A 2026 meta-analysis of 7 studies found lower acne severity, and 5% gel worked more slowly than 5% benzoyl peroxide but caused fewer side effects. Use a diluted product, not the neat oil, and patch-test first.

What are the side effects of tea tree oil?

On skin, redness, dryness and itching are the usual effects, and contact allergy is well documented, with positive patch tests in 0.1% to 3.5% of people tested. Oxidised oil is more allergenic. Swallowing it is dangerous: NCCIH lists confusion, unsteadiness, inability to walk and coma.

Can tea tree oil treat nail fungus or head lice?

Not reliably. In one trial 100% oil matched clotrimazole for toenail fungus, but both cleared few infections. For head lice, only a tea tree and lavender oil combination has been tested, and NCCIH says the effect cannot be credited to tea tree oil alone.

Sources (9)

  1. Randomised trial Satchell AC, Saurajen A, Bell C, Barnetson RS. Treatment of dandruff with 5% tea tree oil shampoo. J Am Acad Dermatol. 2002.
  2. Randomised trial Bassett IB, Pannowitz DL, Barnetson RS. A comparative study of tea-tree oil versus benzoylperoxide in the treatment of acne. Med J Aust. 1990.
  3. Meta-analysis Ye Y, Lim JJ, Huang Z, Chew FT. Efficacy and Safety of Melaleuca alternifolia (Tea Tree) Oil for Acne-A Systematic Review and Meta-Analysis. Phytother Res. 2026.
  4. Systematic review Kairey L, Agnew T, Bowles EJ, Barkla BJ, Wardle J, Lauche R. Efficacy and safety of Melaleuca alternifolia (tea tree) oil for human health-A systematic review of randomized controlled trials. Front Pharmacol. 2023.
  5. Randomised trial Buck DS, Nidorf DM, Addino JG. Comparison of two topical preparations for the treatment of onychomycosis: Melaleuca alternifolia (tea tree) oil and clotrimazole. J Fam Pract. 1994.
  6. Randomised trial Barker SC, Altman PM. A randomised, assessor blind, parallel group comparative efficacy trial of three products for the treatment of head lice in children--melaleuca oil and lavender oil, pyrethrins and piperonyl butoxide, and a suffocation product. BMC Dermatol. 2010.
  7. Review de Groot AC, Schmidt E. Tea tree oil: contact allergy and chemical composition. Contact Dermatitis. 2016.
  8. Regulator/health agency National Center for Complementary and Integrative Health. Tea Tree Oil.
  9. Poison centre National Capital Poison Center. Tea tree oil: Remedy and poison.

Reader notes

Experiences and questions from readers, read by an editor before they appear. They are personal accounts, not evidence, and are not medical advice.

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Last reviewed 10 October 2026 · Next review April 2027 · How we rate evidence