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Awaiting clinical review. This page is built from sourced entries but has not yet been signed off by a pharmacist or clinician.

Natural remedies for sleep

A mug of chamomile tea on a bedside table in soft evening light
Direct answer

Melatonin (Moderate, 3) and ashwagandha root extract (Moderate, 3) are the best-supported supplements for sleep, but both effects are modest: melatonin shortened the time to fall asleep by about 7 minutes in a meta-analysis of 19 trials, and NCCIH says the evidence is not strong enough to recommend it for chronic insomnia. Valerian, chamomile, lavender and the rest are Limited (2) or Traditional (1). The caution that matters most is that the sedating herbs add to alcohol and sedative medicines, and most have no pregnancy safety data.

Draft, awaiting clinical review·2 sources·Built from 14 rated ingredients
Evidence scale:StrongModerateLimitedTraditional

Compare the options

Click a column heading to sort.

Rated forTypical form & useMain caution
Ashwagandha
Withania somnifera (root)
ModerateSleep and insomniaRoot extract, 250–600 mg a dayRare liver injury; avoid in pregnancy4+ weeks
Melatonin
Hormone, usually made synthetically
ModerateFalling asleep (adults)Oral tablet or capsule, 0.5–5 mgLong-term safety unknown; overdose risk in childrenSame night
Chamomile
Matricaria chamomilla (flower)
LimitedSleep qualityExtract 1,500 mg/day (GAD trials)Avoid if allergic to ragweed or daisy-family plants4+ weeks
Hops
Humulus lupulus (female cone)
LimitedSleep (valerian-hops combination)Valerian-hops combo; EU 125–250 mgMay cause drowsiness; not for pregnancy2 weeks
L-Theanine
Amino acid from tea (Camellia sinensis)
LimitedSleep qualityCapsule or tablet, 200 mgPregnancy and long-term safety data are lackingSame night
Lavender
Lavandula angustifolia (flower, oil)
LimitedSleep quality (aromatherapy)Inhaled essential oil; doses varyLittle pregnancy data; theoretical sedative overlap2 weeks
Lemon Balm
Melissa officinalis (leaf)
LimitedSleep qualityStandardised leaf extract (capsule)May impair driving; avoid in pregnancyAbout a week
Magnesium glycinate
Magnesium bisglycinate (mineral chelate)
LimitedPoor sleep / insomnia symptomsBisglycinate, 250 mg elemental MgLoose stools above about 250–350 mg supplemental Mg4+ weeks
Passionflower
Passiflora incarnata (aerial parts)
LimitedInsomniaExtract (2 weeks); tea up to 7 nightsMay add to anaesthetics and sedatives; not in pregnancy2 weeks
Saffron
Crocus sativus (stigma)
LimitedSleep qualityStigma extract, 28–30 mg dailyNot for pregnancy; toxic in multi-gram doses4+ weeks
Tart Cherry
Prunus cerasus (Montmorency fruit)
LimitedSleepConcentrate (7.5–30 ml, twice daily)Not a substitute for gout treatmentAbout a week
Valerian
Valeriana officinalis (root)
LimitedSleep quality and insomniaRoot extract, 300–600 mg at nightAdds to alcohol and sedatives; not for pregnancy2 weeks
Holy basil (tulsi)
Ocimum tenuiflorum (leaf)
TraditionalSleep qualityLeaf extract, 125 mg twice dailyLong-term safety unstudied; check with diabetes drugs4+ weeks
Skullcap
Scutellaria lateriflora (aerial parts)
TraditionalSleep and general nervous tensionDried herb, 350 mg three times dailyLiver injury reported; germander adulteration2 weeks
Sorted by evidence
Ashwagandha
Withania somnifera (root)
Moderate
Rated for
Sleep and insomnia
Form
Root extract, 250–600 mg a day
Onset
4+ weeks
Caution · Rare liver injury; avoid in pregnancy
Melatonin
Hormone, usually made synthetically
Moderate
Rated for
Falling asleep (adults)
Form
Oral tablet or capsule, 0.5–5 mg
Onset
Same night
Caution · Long-term safety unknown; overdose risk in children
Chamomile
Matricaria chamomilla (flower)
Limited
Rated for
Sleep quality
Form
Extract 1,500 mg/day (GAD trials)
Onset
4+ weeks
Caution · Avoid if allergic to ragweed or daisy-family plants
Hops
Humulus lupulus (female cone)
Limited
Rated for
Sleep (valerian-hops combination)
Form
Valerian-hops combo; EU 125–250 mg
Onset
2 weeks
Caution · May cause drowsiness; not for pregnancy
L-Theanine
Amino acid from tea (Camellia sinensis)
Limited
Rated for
Sleep quality
Form
Capsule or tablet, 200 mg
Onset
Same night
Caution · Pregnancy and long-term safety data are lacking
Lavender
Lavandula angustifolia (flower, oil)
Limited
Rated for
Sleep quality (aromatherapy)
Form
Inhaled essential oil; doses vary
Onset
2 weeks
Caution · Little pregnancy data; theoretical sedative overlap
Lemon Balm
Melissa officinalis (leaf)
Limited
Rated for
Sleep quality
Form
Standardised leaf extract (capsule)
Onset
About a week
Caution · May impair driving; avoid in pregnancy
Magnesium glycinate
Magnesium bisglycinate (mineral chelate)
Limited
Rated for
Poor sleep / insomnia symptoms
Form
Bisglycinate, 250 mg elemental Mg
Onset
4+ weeks
Caution · Loose stools above about 250–350 mg supplemental Mg
Passionflower
Passiflora incarnata (aerial parts)
Limited
Rated for
Insomnia
Form
Extract (2 weeks); tea up to 7 nights
Onset
2 weeks
Caution · May add to anaesthetics and sedatives; not in pregnancy
Saffron
Crocus sativus (stigma)
Limited
Rated for
Sleep quality
Form
Stigma extract, 28–30 mg daily
Onset
4+ weeks
Caution · Not for pregnancy; toxic in multi-gram doses
Tart Cherry
Prunus cerasus (Montmorency fruit)
Limited
Rated for
Sleep
Form
Concentrate (7.5–30 ml, twice daily)
Onset
About a week
Caution · Not a substitute for gout treatment
Valerian
Valeriana officinalis (root)
Limited
Rated for
Sleep quality and insomnia
Form
Root extract, 300–600 mg at night
Onset
2 weeks
Caution · Adds to alcohol and sedatives; not for pregnancy
Holy basil (tulsi)
Ocimum tenuiflorum (leaf)
Traditional
Rated for
Sleep quality
Form
Leaf extract, 125 mg twice daily
Onset
4+ weeks
Caution · Long-term safety unstudied; check with diabetes drugs
Skullcap
Scutellaria lateriflora (aerial parts)
Traditional
Rated for
Sleep and general nervous tension
Form
Dried herb, 350 mg three times daily
Onset
2 weeks
Caution · Liver injury reported; germander adulteration

Quick picks

Safety

Talk to a doctor first if…

Who should avoid

Avoid sleep supplements in pregnancy and breastfeeding unless a clinician has agreed: melatonin, valerian, hops, lavender, lemon balm, passionflower and ashwagandha all lack safety data or carry regulator or NCCIH advice against use. Do not drive after taking the sedating herbs, and do not give melatonin to children without clinician advice; keep all products locked away. Anyone with liver disease should avoid ashwagandha and skullcap, both linked to rare liver injury.

Known interactions

Ashwagandha, valerian, passionflower and lavender may add to sedatives, and NCCIH advises against valerian with alcohol or sedatives. Melatonin and chamomile can interact with warfarin and other blood thinners, so ask a prescriber first. Ashwagandha may add to thyroid replacement and immunosuppressants, and holy basil may add to diabetes medicines.

Check your combination

Before you reach for an ingredient

For long-standing sleep trouble, change habits and consider cognitive behavioural therapy for insomnia (CBT-I) first, then use a supplement as a short-term extra if at all.

  • CBT-I has the strongest evidence of any option for chronic insomnia. A meta-analysis of 20 trials (1,162 adults) found it shortened the time to fall asleep by about 19 minutes and time awake in the night by about 26 minutes, with gains that seemed to last and no adverse outcomes reported. The NHS says a GP may offer it face to face or as an online programme.1,2
  • The NHS advises getting up at the same time every day (including after a bad night), going to bed only when sleepy, and winding down for at least an hour beforehand. Its list of things to avoid is no tea, coffee, alcohol or smoking for at least 6 hours before bed, no big late meal, no daytime naps, and no exercise within 4 hours of bed.2
  • Make the bedroom dark, quiet and comfortable, and keep phones and televisions out of the last stretch before bed, because the NHS says their blue light makes you more awake. Pharmacy sleep aids, including those with valerian or lavender, are advised only for 1 to 2 weeks; if sleep has been poor for months, see a GP.2

Questions people ask

Does melatonin work for insomnia?

A little. A meta-analysis of 19 placebo-controlled trials found people fell asleep about 7 minutes faster and slept about 8 minutes longer. NCCIH says the evidence is not strong enough to recommend it for chronic insomnia, and its long-term safety is unknown.

What is the best natural sleep aid?

No herb or supplement is proven to be strong. Melatonin and ashwagandha root extract are the two rated Moderate (3), and both give modest gains. For long-term insomnia, CBT-I has better evidence than any supplement.

Does valerian help you sleep?

It may help you feel you slept better, but the measured effect is not there: time to fall asleep differed by 0.70 minutes from placebo, and a 2024 umbrella review found no evidence of efficacy for insomnia. Do not combine it with alcohol or sedatives.

Is it safe to take sleep supplements every night?

Nobody knows for most of them. Melatonin's long-term safety has not been established, and ashwagandha has been studied for about three months at most. The NHS advises pharmacy sleep aids for 1 to 2 weeks only.

Sources

  1. Systematic review Trauer JM, Qian MY, Doyle JS, Rajaratnam SM, Cunnington D. Cognitive Behavioral Therapy for Chronic Insomnia: A Systematic Review and Meta-analysis. Ann Intern Med. 2015.
  2. Health service guidance NHS. Insomnia. NHS website.

Draft, awaiting clinical review

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